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4j2q
From Proteopedia
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| - | + | {{STRUCTURE_4j2q| PDB=4j2q | SCENE= }} | |
| + | ===Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation=== | ||
| + | {{ABSTRACT_PUBMED_23604253}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Note=S-antigen induces autoimmune uveitis. | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade. | ||
| - | + | ==About this Structure== | |
| + | [[4j2q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2Q OCA]. | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Choe, H W.]] | ||
| + | [[Category: Kim, Y J.]] | ||
| + | [[Category: Scheerer, P.]] | ||
| + | [[Category: Arrestin fold]] | ||
| + | [[Category: Deactivation]] | ||
| + | [[Category: G-protein]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Outer segment]] | ||
| + | [[Category: P44]] | ||
| + | [[Category: Rhodopsin]] | ||
| + | [[Category: S-antigen]] | ||
| + | [[Category: Signal termination]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Splice variant mutant arrestin]] | ||
| + | [[Category: Visual signal transduction]] | ||
Revision as of 07:38, 2 May 2013
Contents |
Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation
Template:ABSTRACT PUBMED 23604253
Disease
[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
Function
[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
About this Structure
4j2q is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
