4jak

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4jak| PDB=4jak | SCENE= }}
 +
===Crystal structure of tRNA (Um34/Cm34) methyltransferase TrmL from Escherichia coli===
 +
{{ABSTRACT_PUBMED_23804755}}
-
The entry 4jak is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/TRML_ECOLI TRML_ECOLI]] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Recognition of the target requires a pyridine at position 34 and N(6)-(isopentenyl)-2-methylthioadenosine at position 37.<ref>PMID:20855540</ref>
-
Authors: Liu, R.J., Zhou, M., Wang, E.D.
+
==About this Structure==
 +
[[4jak]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JAK OCA].
-
Description: Crystal structure of tRNA (Um34/Cm34) methyltransferase TrmL from Escherichia coli
+
==Reference==
 +
<ref group="xtra">PMID:023804755</ref><references group="xtra"/><references/>
 +
[[Category: Escherichia coli k-12]]
 +
[[Category: Liu, R J.]]
 +
[[Category: Wang, E D.]]
 +
[[Category: Zhou, M.]]
 +
[[Category: Deep trefoil knot]]
 +
[[Category: Methylation]]
 +
[[Category: Methyltransferase]]
 +
[[Category: Sam binding]]
 +
[[Category: Spout]]
 +
[[Category: Transferase]]
 +
[[Category: Trna modification]]

Revision as of 05:20, 1 August 2013

Template:STRUCTURE 4jak

Contents

Crystal structure of tRNA (Um34/Cm34) methyltransferase TrmL from Escherichia coli

Template:ABSTRACT PUBMED 23804755

Function

[TRML_ECOLI] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Recognition of the target requires a pyridine at position 34 and N(6)-(isopentenyl)-2-methylthioadenosine at position 37.[1]

About this Structure

4jak is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Liu RJ, Zhou M, Fang ZP, Wang M, Zhou XL, Wang ED. The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL. Nucleic Acids Res. 2013 Jun 26. PMID:23804755 doi:10.1093/nar/gkt568
  1. ↑ Benitez-Paez A, Villarroya M, Douthwaite S, Gabaldon T, Armengod ME. YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors. RNA. 2010 Nov;16(11):2131-43. doi: 10.1261/rna.2245910. Epub 2010 Sep 20. PMID:20855540 doi:10.1261/rna.2245910

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4jak"
Personal tools