4jbx
From Proteopedia
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{{STRUCTURE_4jbx| PDB=4jbx | SCENE= }} | {{STRUCTURE_4jbx| PDB=4jbx | SCENE= }} | ||
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===Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with SK-78=== | ===Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with SK-78=== | ||
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{{ABSTRACT_PUBMED_21623543}} | {{ABSTRACT_PUBMED_21623543}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/KITH_HHV11 KITH_HHV11]] In latent infection, may allow the virus to be reactivated and to grow in cells lacking a high concentration of phosphorylated nucleic acid precursors, such as nerve cells that do not replicate their genome (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[4jbx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Herpes_simplex_virus_(type_1_/_strain_17) Herpes simplex virus (type 1 / strain 17)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBX OCA]. | [[4jbx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Herpes_simplex_virus_(type_1_/_strain_17) Herpes simplex virus (type 1 / strain 17)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBX OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Thymidine kinase|Thymidine kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:021623543</ref><references group="xtra"/> | + | <ref group="xtra">PMID:021623543</ref><references group="xtra"/><references/> |
[[Category: Thymidine kinase]] | [[Category: Thymidine kinase]] | ||
[[Category: Novakovic, I.]] | [[Category: Novakovic, I.]] | ||
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[[Category: Raic-Malic, S.]] | [[Category: Raic-Malic, S.]] | ||
[[Category: Scapozza, L.]] | [[Category: Scapozza, L.]] | ||
| + | [[Category: Westermaier, Y.]] | ||
[[Category: Atp binding]] | [[Category: Atp binding]] | ||
[[Category: Dna synthesis]] | [[Category: Dna synthesis]] | ||
Revision as of 05:55, 2 October 2013
Contents |
Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with SK-78
Template:ABSTRACT PUBMED 21623543
Function
[KITH_HHV11] In latent infection, may allow the virus to be reactivated and to grow in cells lacking a high concentration of phosphorylated nucleic acid precursors, such as nerve cells that do not replicate their genome (By similarity).
About this Structure
4jbx is a 2 chain structure with sequence from Herpes simplex virus (type 1 / strain 17). Full crystallographic information is available from OCA.
See Also
Reference
- Martic M, Pernot L, Westermaier Y, Perozzo R, Kraljevic TG, Kristafor S, Raic-Malic S, Scapozza L, Ametamey S. Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. Nucleosides Nucleotides Nucleic Acids. 2011 Apr;30(4):293-315. PMID:21623543 doi:10.1080/15257770.2011.581258
