This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3hht
From Proteopedia
(Difference between revisions)
m (Protected "3hht" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[ | + | ==A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability== |
| + | <StructureSection load='3hht' size='340' side='right' caption='[[3hht]], [[Resolution|resolution]] 1.16Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3hht]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeribacillus_pallidus Aeribacillus pallidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HHT FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3CO:COBALT+(III)+ION'>3CO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitrile_hydratase Nitrile hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.84 4.2.1.84] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hht OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hht RCSB], [http://www.ebi.ac.uk/pdbsum/3hht PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hht_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Nitrile hydratase|Nitrile hydratase]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | [[ | + | |
[[Category: Aeribacillus pallidus]] | [[Category: Aeribacillus pallidus]] | ||
[[Category: Nitrile hydratase]] | [[Category: Nitrile hydratase]] | ||
| - | [[Category: Bishop, A O.Tastan | + | [[Category: Bishop, A O.Tastan]] |
| - | [[Category: Cowan, D A | + | [[Category: Cowan, D A]] |
| - | [[Category: Sayed, M F | + | [[Category: Sayed, M F]] |
| - | [[Category: Sewell, B T | + | [[Category: Sewell, B T]] |
| - | [[Category: Tsekoa, T L | + | [[Category: Tsekoa, T L]] |
| - | [[Category: Wyk, J C.Van | + | [[Category: Wyk, J C.Van]] |
[[Category: Lyase]] | [[Category: Lyase]] | ||
Revision as of 09:04, 20 January 2015
A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability
| |||||||||||

