1ffk

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{{STRUCTURE_1ffk| PDB=1ffk | SCENE= }}
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==CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION==
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===CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION===
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<StructureSection load='1ffk' size='340' side='right' caption='[[1ffk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{ABSTRACT_PUBMED_10937989}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ffk]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. The October 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ribosome'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_10 10.2210/rcsb_pdb/mom_2000_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFK FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c04|1c04]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffk RCSB], [http://www.ebi.ac.uk/pdbsum/1ffk PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The large ribosomal subunit catalyzes peptide bond formation and binds initiation, termination, and elongation factors. We have determined the crystal structure of the large ribosomal subunit from Haloarcula marismortui at 2.4 angstrom resolution, and it includes 2833 of the subunit's 3045 nucleotides and 27 of its 31 proteins. The domains of its RNAs all have irregular shapes and fit together in the ribosome like the pieces of a three-dimensional jigsaw puzzle to form a large, monolithic structure. Proteins are abundant everywhere on its surface except in the active site where peptide bond formation occurs and where it contacts the small subunit. Most of the proteins stabilize the structure by interacting with several RNA domains, often using idiosyncratically folded extensions that reach into the subunit's interior.
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==About this Structure==
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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.,Ban N, Nissen P, Hansen J, Moore PB, Steitz TA Science. 2000 Aug 11;289(5481):905-20. PMID:10937989<ref>PMID:10937989</ref>
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[[1ffk]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. The October 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ribosome'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_10 10.2210/rcsb_pdb/mom_2000_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFK OCA].
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
==See Also==
==See Also==
*[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]]
*[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]]
*[[Nobel Prizes for 3D Molecular Structure|Nobel Prizes for 3D Molecular Structure]]
*[[Nobel Prizes for 3D Molecular Structure|Nobel Prizes for 3D Molecular Structure]]
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*[[Ribosomal protein L10|Ribosomal protein L10]]
 
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*[[Ribosomal protein L13|Ribosomal protein L13]]
 
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*[[Ribosomal protein L14|Ribosomal protein L14]]
 
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*[[Ribosomal protein L15|Ribosomal protein L15]]
 
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*[[Ribosomal protein L18|Ribosomal protein L18]]
 
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*[[Ribosomal protein L19|Ribosomal protein L19]]
 
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*[[Ribosomal protein L2|Ribosomal protein L2]]
 
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*[[Ribosomal protein L21|Ribosomal protein L21]]
 
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*[[Ribosomal protein L22|Ribosomal protein L22]]
 
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*[[Ribosomal protein L23|Ribosomal protein L23]]
 
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*[[Ribosomal protein L24|Ribosomal protein L24]]
 
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*[[Ribosomal protein L29|Ribosomal protein L29]]
 
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*[[Ribosomal protein L3|Ribosomal protein L3]]
 
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*[[Ribosomal protein L30|Ribosomal protein L30]]
 
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*[[Ribosomal protein L34|Ribosomal protein L34]]
 
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*[[Ribosomal protein L4|Ribosomal protein L4]]
 
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*[[Ribosomal protein L5|Ribosomal protein L5]]
 
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*[[Ribosomal protein L6|Ribosomal protein L6]]
 
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*[[Ribosomal protein L7|Ribosomal protein L7]]
 
*[[Ribosome|Ribosome]]
*[[Ribosome|Ribosome]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
*[[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|User:Wayne Decatur/Haloarcula Large Ribosomal Subunit]]
*[[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|User:Wayne Decatur/Haloarcula Large Ribosomal Subunit]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010937989</ref><ref group="xtra">PMID:011296253</ref><ref group="xtra">PMID:012511960</ref><ref group="xtra">PMID:014566331</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]

Revision as of 14:13, 29 September 2014

CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION

1ffk, resolution 2.40Å

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