This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3gkl
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ==Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins== | |
| - | + | <StructureSection load='3gkl' size='340' side='right' caption='[[3gkl]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3gkl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GKL FirstGlance]. <br> | |
| - | == | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[3gkl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GKL OCA]. | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gjn|3gjn]]</td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">colE7, cea ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), imm, ceiE9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gkl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gkl RCSB], [http://www.ebi.ac.uk/pdbsum/3gkl PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/3gkl_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 27: | ||
*[[Mutant immunity protein 9 (variant R12-13)|Mutant immunity protein 9 (variant R12-13)]] | *[[Mutant immunity protein 9 (variant R12-13)|Mutant immunity protein 9 (variant R12-13)]] | ||
*[[Mutant immunity protein 9 (variant R12-2)|Mutant immunity protein 9 (variant R12-2)]] | *[[Mutant immunity protein 9 (variant R12-2)|Mutant immunity protein 9 (variant R12-2)]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Dym, O | + | [[Category: Dym, O]] |
| - | [[Category: ISPC, Israel Structural Proteomics Center | + | [[Category: ISPC, Israel Structural Proteomics Center]] |
| - | [[Category: Tawfik, D S | + | [[Category: Tawfik, D S]] |
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Antimicrobial]] | [[Category: Antimicrobial]] | ||
| Line 27: | Line 39: | ||
[[Category: Endonuclease]] | [[Category: Endonuclease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: ISPC]] | ||
| - | [[Category: Israel Structural Proteomics Center]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Nuclease]] | [[Category: Nuclease]] | ||
[[Category: Protein-protein complex]] | [[Category: Protein-protein complex]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
Revision as of 06:33, 18 December 2014
Following evolutionary paths to high affinity and selectivity protein-protein interactions using Colicin7 and Immunity proteins
| |||||||||||
