3odv
From Proteopedia
(Difference between revisions)
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| - | + | ==X-ray structure of kaliotoxin by racemic protein crystallography== | |
| - | + | <StructureSection load='3odv' size='340' side='right' caption='[[3odv]], [[Resolution|resolution]] 0.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3odv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ODV FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=TFA:TRIFLUOROACETIC+ACID'>TFA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3odv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3odv RCSB], [http://www.ebi.ac.uk/pdbsum/3odv PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Here we report the total synthesis of kaliotoxin by 'one pot' native chemical ligation of three synthetic peptides. A racemic mixture of d- and l-kaliotoxin synthetic protein molecules gave crystals in the centrosymmetric space group P1[combining macron] that diffracted to atomic-resolution (0.95 A), enabling the X-ray structure of kaliotoxin to be determined by direct methods. | ||
| - | + | Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.,Pentelute BL, Mandal K, Gates ZP, Sawaya MR, Yeates TO, Kent SB Chem Commun (Camb). 2010 Sep 28. PMID:20877851<ref>PMID:20877851</ref> | |
| - | + | ||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
==See Also== | ==See Also== | ||
*[[Potassium channel toxin|Potassium channel toxin]] | *[[Potassium channel toxin|Potassium channel toxin]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| - | [[Category: Gates, Z P | + | </StructureSection> |
| - | [[Category: Kent, S B.H | + | [[Category: Gates, Z P]] |
| - | [[Category: Mandal, K | + | [[Category: Kent, S B.H]] |
| - | [[Category: Pentelute, B L | + | [[Category: Mandal, K]] |
| - | [[Category: Sawaya, M R | + | [[Category: Pentelute, B L]] |
| - | [[Category: Yeates, T O | + | [[Category: Sawaya, M R]] |
| + | [[Category: Yeates, T O]] | ||
[[Category: Chemical synthesis]] | [[Category: Chemical synthesis]] | ||
[[Category: Direct method]] | [[Category: Direct method]] | ||
[[Category: Racemic protein]] | [[Category: Racemic protein]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
Revision as of 08:47, 18 December 2014
X-ray structure of kaliotoxin by racemic protein crystallography
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