2bjo
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:2bjo.gif|left|200px]] | + | [[Image:2bjo.gif|left|200px]] |
| - | + | ||
| - | '''CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS''' | + | {{Structure |
| + | |PDB= 2bjo |SIZE=350|CAPTION= <scene name='initialview01'>2bjo</scene>, resolution 2.101Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2BJO is a [ | + | 2BJO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJO OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:[http:// | + | Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18084074 18084074] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 23: | Line 32: | ||
[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:02:49 2008'' |
Revision as of 14:02, 20 March 2008
| |||||||
| , resolution 2.101Å | |||||||
|---|---|---|---|---|---|---|---|
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS
Overview
The crystal structure of the fully oxidized form of the Bacillus subtilis organic hydroperoxide-resistance (OhrB) protein is reported at 2.1 A resolution. The electron density reveals an intact catalytic disulfide bond (Cys55-Cys119) in each of the two molecules, which are intertwined into a canonical obligate dimer. However, the stereochemistry of the disulfides is unorthodox and strained, suggesting that they are sensitive to reducing agents. A deep solvent-accessible gorge reaching Cys55 may represent the access route for the reductant.
About this Structure
2BJO is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:18084074
Page seeded by OCA on Thu Mar 20 16:02:49 2008
