2bjo

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[[Image:2bjo.gif|left|200px]]<br /><applet load="2bjo" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2bjo.gif|left|200px]]
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caption="2bjo, resolution 2.101&Aring;" />
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'''CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS'''<br />
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{{Structure
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|PDB= 2bjo |SIZE=350|CAPTION= <scene name='initialview01'>2bjo</scene>, resolution 2.101&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2BJO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJO OCA].
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2BJO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJO OCA].
==Reference==
==Reference==
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Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18084074 18084074]
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Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18084074 18084074]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:38:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:02:49 2008''

Revision as of 14:02, 20 March 2008


PDB ID 2bjo

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, resolution 2.101Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS


Overview

The crystal structure of the fully oxidized form of the Bacillus subtilis organic hydroperoxide-resistance (OhrB) protein is reported at 2.1 A resolution. The electron density reveals an intact catalytic disulfide bond (Cys55-Cys119) in each of the two molecules, which are intertwined into a canonical obligate dimer. However, the stereochemistry of the disulfides is unorthodox and strained, suggesting that they are sensitive to reducing agents. A deep solvent-accessible gorge reaching Cys55 may represent the access route for the reductant.

About this Structure

2BJO is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:18084074

Page seeded by OCA on Thu Mar 20 16:02:49 2008

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