2bkf

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[[Image:2bkf.gif|left|200px]]<br /><applet load="2bkf" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2bkf.gif|left|200px]]
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caption="2bkf, resolution 1.56&Aring;" />
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'''STRUCTURE OF THE PB1 DOMAIN OF NBR1'''<br />
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{{Structure
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|PDB= 2bkf |SIZE=350|CAPTION= <scene name='initialview01'>2bkf</scene>, resolution 1.56&Aring;
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|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''STRUCTURE OF THE PB1 DOMAIN OF NBR1'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2BKF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKF OCA].
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2BKF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKF OCA].
==Reference==
==Reference==
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Crystal structure of the PB1 domain of NBR1., Muller S, Kursula I, Zou P, Wilmanns M, FEBS Lett. 2006 Jan 9;580(1):341-4. Epub 2005 Dec 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16376336 16376336]
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Crystal structure of the PB1 domain of NBR1., Muller S, Kursula I, Zou P, Wilmanns M, FEBS Lett. 2006 Jan 9;580(1):341-4. Epub 2005 Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16376336 16376336]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: zinc-finger]]
[[Category: zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:38:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:03:07 2008''

Revision as of 14:03, 20 March 2008

Image:2bkf.gif


PDB ID 2bkf

Drag the structure with the mouse to rotate
, resolution 1.56Å
Sites:
Ligands:
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF THE PB1 DOMAIN OF NBR1


Overview

The scaffold protein NBR1 is involved in signal transmission downstream of the serine/protein kinase from the giant muscle protein titin. Its N-terminal Phox and Bem1p (PB1) domain plays a critical role in mediating protein-protein interactions with both titin kinase and with another scaffold protein, p62. We have determined the crystal structure of the PB1 domain of NBR1 at 1.55A resolution. It reveals a type-A PB1 domain with two negatively charged residue clusters. We provide a structural perspective on the involvement of NBR1 in the titin kinase signalling pathway.

About this Structure

2BKF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the PB1 domain of NBR1., Muller S, Kursula I, Zou P, Wilmanns M, FEBS Lett. 2006 Jan 9;580(1):341-4. Epub 2005 Dec 19. PMID:16376336

Page seeded by OCA on Thu Mar 20 16:03:07 2008

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