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4e68
From Proteopedia
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===Unphosphorylated STAT3B core protein binding to dsDNA=== | ===Unphosphorylated STAT3B core protein binding to dsDNA=== | ||
{{ABSTRACT_PUBMED_23434585}} | {{ABSTRACT_PUBMED_23434585}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/STAT3_MOUSE STAT3_MOUSE]] Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. STAT3B interacts with the N-terminal part of JUN to activate such promoters in a cooperative way.<ref>PMID:11294897</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[4e68]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E68 OCA]. | [[4e68]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E68 OCA]. | ||
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| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Collie, G W.]] | [[Category: Collie, G W.]] | ||
Revision as of 21:44, 10 April 2013
Contents |
Unphosphorylated STAT3B core protein binding to dsDNA
Template:ABSTRACT PUBMED 23434585
Function
[STAT3_MOUSE] Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. STAT3B interacts with the N-terminal part of JUN to activate such promoters in a cooperative way.[1]
About this Structure
4e68 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
