3ow3

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Revision as of 09:30, 13 March 2013

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Template:STRUCTURE 3ow3

Contents 1 Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors 2 About this Structure 3 See Also 4 Reference

Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

Template:ABSTRACT PUBMED 20971641

About this Structure

3ow3 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• CAMP-dependent protein kinase

Reference

• Bencsik JR, Xiao D, Blake JF, Kallan NC, Mitchell IS, Spencer KL, Xu R, Gloor SL, Martinson M, Risom T, Woessner RD, Dizon F, Wu WI, Vigers GP, Brandhuber BJ, Skelton NJ, Prior WW, Murray LJ. Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7037-41. Epub 2010 Sep 29. PMID:20971641 doi:10.1016/j.bmcl.2010.09.112