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4efk

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{{STRUCTURE_4efk| PDB=4efk | SCENE= }}
{{STRUCTURE_4efk| PDB=4efk | SCENE= }}
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===Pantothenate synthetase in complex with fragment 11===
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===Pantothenate synthetase in complex with N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE===
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==Function==
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[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
==About this Structure==
==About this Structure==
[[4efk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EFK OCA].
[[4efk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EFK OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantoate--beta-alanine ligase]]
[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Abell, C]]
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[[Category: Abell, C.]]
[[Category: Blundell, T L.]]
[[Category: Blundell, T L.]]
[[Category: Ciulli, A.]]
[[Category: Ciulli, A.]]

Revision as of 12:34, 3 July 2013

Template:STRUCTURE 4efk

Contents

Pantothenate synthetase in complex with N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE

Function

[PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[1]

About this Structure

4efk is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. ↑ Zheng R, Blanchard JS. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase. Biochemistry. 2001 Oct 30;40(43):12904-12. PMID:11669627

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