3ijj

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Revision as of 10:38, 13 March 2013

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Template:STRUCTURE 3ijj

Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)

Template:ABSTRACT PUBMED 20534506

About this Structure

3ijj is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. Epub 2010 Jun 8. PMID:20534506