We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
3idp
From Proteopedia
(Difference between revisions)
m (Protected "3idp" [edit=sysop:move=sysop]) |
Revision as of 11:02, 13 March 2013
B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
Template:ABSTRACT PUBMED 19764794
About this Structure
3idp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Smith AL, Demorin FF, Paras NA, Huang Q, Petkus JK, Doherty EM, Nixey T, Kim JL, Whittington DA, Epstein LF, Lee MR, Rose MJ, Babij C, Fernando M, Hess K, Le Q, Beltran P, Carnahan J. Selective Inhibitors of the Mutant B-Raf Pathway: Discovery of a Potent and Orally Bioavailable Aminoisoquinoline. J Med Chem. 2009 Sep 18. PMID:19764794 doi:10.1021/jm901081g
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Epstein, L F. | Whittington, D A. | Atp-binding | Cardiomyopathy | Dfg-out | Disease mutation | Kinase | Metal-binding | Nucleotide-binding | Oncogene | Phorbol-ester binding | Phosphoprotein | Proto-oncogene | Serine/threonine-protein kinase | Transferase | Zinc-finger
