Outer surface protein
From Proteopedia
(Difference between revisions)
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'''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | '''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | ||
| - | OspA - [[OspA]] | + | OspA - <br /> |
| - | OspB - [[Outer surface protein B (OspB) of the Lyme disease spirochete bacterium]]<br /> | + | *[[OspA]]<br /> |
| - | [[G15SecL05Tpc3]]<br /> | + | *[[G09SecL04Tpc2]]<br /> |
| - | [[G14secL04Tpc3]]<br /> | + | *[[G1SecL05]]<br /> |
| - | OspC - [[OspC and Binding]]<br /> | + | OspB - <br /> |
| - | [[G18secL03Tpc4]]. | + | *[[Outer surface protein B (OspB) of the Lyme disease spirochete bacterium]]<br /> |
| + | *[[G15SecL05Tpc3]]<br /> | ||
| + | *[[G14secL04Tpc3]]<br /> | ||
| + | OspC - <br /> | ||
| + | *[[OspC and Binding]]<br /> | ||
| + | *[[G18secL03Tpc4]]. | ||
===OspA=== | ===OspA=== | ||
Revision as of 08:26, 4 July 2013
Contents |
3D structures of outer surface protein
Outer surface proteins (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:
OspA -
OspB -
OspC -
OspA
1osp, 1fj1 – OspA (mutant) + antibody – Borrelia burgdorferi
2af5, 2fkg, 2fkj, 2hkd – OspA
2g8c, 2i5z, 2ol6, 2ol7, 2ol8, 2oy1, 2i5v, 2oy5, 2oy7, 2oy8 - OspA (mutant)
OspB
1p4p – OspB C terminal
1rjl - OspB+ antibody
OspC
1ggq, 1g5z – OspC
1f1m – OspC (mutant)
