Hormone
From Proteopedia
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* [[Estrogen-related receptor]] | * [[Estrogen-related receptor]] | ||
* [[Leucine-rich repeat|Leucine-rich repeat proteins]] | * [[Leucine-rich repeat|Leucine-rich repeat proteins]] | ||
| + | * [[Human growth hormone]] | ||
* [[Vascular Endothelial Growth Factor]] | * [[Vascular Endothelial Growth Factor]] | ||
* [[Vascular Endothelial Growth Factor Receptor]] | * [[Vascular Endothelial Growth Factor Receptor]] | ||
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|COORDINATES= | |COORDINATES= | ||
}} | }} | ||
| + | [[Human Follicle-Stimulating Hormone Complexed with its Receptor]] is featured [[Human Follicle-Stimulating Hormone Complexed with its Receptor|here]].<br /> | ||
[[4ay9]] - Human Follicle Stimulating Hormone complexed with the entire ectodomain of its receptor – human<br /> | [[4ay9]] - Human Follicle Stimulating Hormone complexed with the entire ectodomain of its receptor – human<br /> | ||
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===Growth Hormone=== | ===Growth Hormone=== | ||
| + | [[Human growth hormone]] is featured [[Human growth hormone|here]].<br /> | ||
[[3hhr]] - Growth Hormone complexed with the extracellular portion of its receptor - human<br /> | [[3hhr]] - Growth Hormone complexed with the extracellular portion of its receptor - human<br /> | ||
| - | [[1hwh]] - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br /> | + | [[1hwh]],[[1a22]] - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br /> |
[[1bp3]] - Growth Hormone complexed with the prolactin receptor - human<br /> | [[1bp3]] - Growth Hormone complexed with the prolactin receptor - human<br /> | ||
[[3mjg]], [[3mjk]] - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human<br /> | [[3mjg]], [[3mjk]] - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human<br /> | ||
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Vascular Endothelial Growth Factor Receptor – human, see [[VEGFR#Additional_3D_Structures_of_VEGFR|Vascular Endothelial Growth Factor Receptor Structures]]<br /> | Vascular Endothelial Growth Factor Receptor – human, see [[VEGFR#Additional_3D_Structures_of_VEGFR|Vascular Endothelial Growth Factor Receptor Structures]]<br /> | ||
[[2xdg]] - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human<br /> | [[2xdg]] - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human<br /> | ||
| + | [[1axi]] – HGH (mutant) + HGH receptor (mutant)<br /> | ||
===Insulin=== | ===Insulin=== | ||
Revision as of 20:07, 3 April 2013
In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.
Guide to Proteopedia Pages Concerning Hormones and their Receptors
Articles in Proteopedia concerning Hormone include:
To view automatically seeded indices concerning Hormone, see:
Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules
Adrenaline
Beta-2 Adrenergic Receptor
The human β2 adrenergic receptor bound to a hormone analog and G-protein (3sn6) is featured in an image on the right, and additional structures are on the Adrenergic receptor page.
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Angiotensinogen
2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse
Chorionic Gonadotropin
1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human
Estrogen-related receptor
Estrogen-related receptor – human and others, see Estrogen-related receptor structures
Farnesoid X Receptor
3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human
Follicle-Stimulating Hormone
1fl7 - Follicle-Stimulating Hormone – human
1xwd - Human Follicle Stimulating Hormone complexed with the Leucine-repeat region of the binding domain of its receptor– human
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| FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor (1fl7 morphing to 1xwd, resolution 2.92Å) | |||||||
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Human Follicle-Stimulating Hormone Complexed with its Receptor is featured here.
4ay9 - Human Follicle Stimulating Hormone complexed with the entire ectodomain of its receptor – human
PACAP/glucagon family of peptide hormones
3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular
Glucocorticoid
3mne, 3mno, 3mnp - Glucocorticoid Receptor Ligand-binding Domain – human
Glucose-dependent Insulinotropic Polypeptide
Glucose-dependent Insulinotropic Polypeptide Receptor
Growth Hormone
Human growth hormone is featured here.
3hhr - Growth Hormone complexed with the extracellular portion of its receptor - human
1hwh,1a22 - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human
1bp3 - Growth Hormone complexed with the prolactin receptor - human
3mjg, 3mjk - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human
Vascular Endothelial Growth Factor – human and others, see Vascular Endothelial Growth Factor Structures
Vascular Endothelial Growth Factor Receptor – human, see Vascular Endothelial Growth Factor Receptor Structures
2xdg - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human
1axi – HGH (mutant) + HGH receptor (mutant)
Insulin
3ir0 , 1mso , 1trz , 2qiu , 2r34, 2r35 , 2r36, 3ilg, 2kjj , 2kju - Insulin – human
3nw5, 3nw6, 3nw7 - insulin-like growth factor 1 receptor – human
3loh, 2dtg - insulin receptor ectodomain – human
Glucose-dependent Insulinotropic Polypeptide Receptor
Progesterone
3hq5,3g8n, 3g8o, 3hq5 - Progesterone – human
Thyroid-Stimulating hormone
3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human
2xwt - TSH receptor in complex with a thyroid-inactivating autoantibody – human
Thyroid hormone
2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx
Thyroxine
2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human
domain of the human splice variant hPAC1-RS determined by NMR - human
ADD 3dzu
See Also
- Cancer
- Membrane proteins
- G protein-coupled receptors
- Nobel Prizes for 3D Molecular Structure
- Highest impact structures of all time
External Resources
- Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors
- GRIS: Glycoprotein-hormone Receptors Information System
- The GPCR-SSFE Database: A Homology Model Resource for G-Protein Coupled Receptors
- The feature on Growth Hormone by Shuchismita Dutta and David S. Goodsell for the April 2004 RCSB PDB Molecule of the Month.
- NeuroPedia, a neuropeptide database and spectral library
Proteopedia Page Contributors and Editors (what is this?)
Wayne Decatur, Alexander Berchansky, Michal Harel, Tomas Klumpler, Joel L. Sussman
