4jhz

(Difference between revisions)

Revision as of 07:31, 28 August 2013

4jhz is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Roberts AB, Wallace BD, Venkatesh MK, Mani S, Redinbo MR. Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity. Mol Pharmacol. 2013 Aug;84(2):208-17. doi: 10.1124/mol.113.085852. Epub 2013 May , 20. PMID:23690068 doi:10.1124/mol.113.085852

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-'''Unreleased structure'''
+{{STRUCTURE_4jhz|  PDB=4jhz  |  SCENE=  }}
+===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-N-[(1S,2S,5S)-2,5-dimethoxycyclohexyl]acetamide===
+{{ABSTRACT_PUBMED_23690068}}
-The entry 4jhz is ON HOLD  until Paper Publication
+==About this Structure==
+[[4jhz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JHZ OCA].
-Authors: Roberts, A.B., Wallace, B.D., Redinbo, M.R.
+==Reference==
+<ref group="xtra">PMID:023690068</ref><references group="xtra"/><references/>
-Description:
+[[Category: Beta-glucuronidase]]
+[[Category: Escherichia coli k-12]]
+[[Category: Redinbo, M R.]]
+[[Category: Roberts, A B.]]
+[[Category: Wallace, B D.]]
+[[Category: Alpha/beta barrel]]
+[[Category: Beta-sandwich domain]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Sugar-binding domain]]