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2cmz
From Proteopedia
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| - | [[Image:2cmz.gif|left|200px]] | + | [[Image:2cmz.gif|left|200px]] |
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| - | '''CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION''' | + | {{Structure |
| + | |PDB= 2cmz |SIZE=350|CAPTION= <scene name='initialview01'>2cmz</scene>, resolution 2.40Å | ||
| + | |SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+C'>AC1</scene> | ||
| + | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2CMZ is a [ | + | 2CMZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vesicular_stomatitis_indiana_virus Vesicular stomatitis indiana virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMZ OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G., Roche S, Bressanelli S, Rey FA, Gaudin Y, Science. 2006 Jul 14;313(5784):187-91. PMID:[http:// | + | Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G., Roche S, Bressanelli S, Rey FA, Gaudin Y, Science. 2006 Jul 14;313(5784):187-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16840692 16840692] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Vesicular stomatitis indiana virus]] | [[Category: Vesicular stomatitis indiana virus]] | ||
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[[Category: transmembrane]] | [[Category: transmembrane]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:17:28 2008'' |
Revision as of 14:17, 20 March 2008
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| , resolution 2.40Å | |||||||
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| Sites: | |||||||
| Ligands: | and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION
Overview
The vesicular stomatitis virus has an atypical membrane fusion glycoprotein (G) exhibiting a pH-dependent equilibrium between two forms at the virus surface. Membrane fusion is triggered during the transition from the high- to low-pH form. The structure of G in its low-pH form shows the classic hairpin conformation observed in all other fusion proteins in their postfusion conformation, in spite of a novel fold combining features of fusion proteins from classes I and II. The structure provides a framework for understanding the reversibility of the G conformational change. Unexpectedly, G is homologous to gB of herpesviruses, which raises important questions on viral evolution.
About this Structure
2CMZ is a Single protein structure of sequence from Vesicular stomatitis indiana virus. Full crystallographic information is available from OCA.
Reference
Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G., Roche S, Bressanelli S, Rey FA, Gaudin Y, Science. 2006 Jul 14;313(5784):187-91. PMID:16840692
Page seeded by OCA on Thu Mar 20 16:17:28 2008
