2cua
From Proteopedia
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| - | [[Image:2cua.jpg|left|200px]] | + | [[Image:2cua.jpg|left|200px]] |
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| - | '''THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS''' | + | {{Structure |
| + | |PDB= 2cua |SIZE=350|CAPTION= <scene name='initialview01'>2cua</scene>, resolution 1.60Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CUA:DINUCLEAR COPPER ION'>CUA</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2CUA is a [ | + | 2CUA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUA OCA]. |
==Reference== | ==Reference== | ||
| - | The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution., Williams PA, Blackburn NJ, Sanders D, Bellamy H, Stura EA, Fee JA, McRee DE, Nat Struct Biol. 1999 Jun;6(6):509-16. PMID:[http:// | + | The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution., Williams PA, Blackburn NJ, Sanders D, Bellamy H, Stura EA, Fee JA, McRee DE, Nat Struct Biol. 1999 Jun;6(6):509-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10360350 10360350] |
[[Category: Cytochrome-c oxidase]] | [[Category: Cytochrome-c oxidase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: cua center]] | [[Category: cua center]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:19:53 2008'' |
Revision as of 14:19, 20 March 2008
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| , resolution 1.60Å | |||||||
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| Ligands: | and | ||||||
| Activity: | Cytochrome-c oxidase, with EC number 1.9.3.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS
Overview
The structure of the CuA-containing, extracellular domain of Thermus thermophilus ba3-type cytochrome c oxidase has been determined to 1.6 A resolution using multiple X-ray wavelength anomalous dispersion (MAD). The Cu2S2 cluster forms a planar rhombus with a copper-copper distance of 2.51 +/- 0.03 A. X-ray absorption fine-structure (EXAFS) studies show that this distance is unchanged by crystallization. The CuA center is asymmetrical; one copper is tetrahedrally coordinated to two bridging cysteine thiolates, one histidine nitrogen and one methionine sulfur, while the other is trigonally coordinated by the two cysteine thiolates and a histidine nitrogen. Combined sequence-structure alignment of amino acid sequences reveals conserved interactions between cytochrome c oxidase subunits I and II.
About this Structure
2CUA is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
Reference
The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution., Williams PA, Blackburn NJ, Sanders D, Bellamy H, Stura EA, Fee JA, McRee DE, Nat Struct Biol. 1999 Jun;6(6):509-16. PMID:10360350
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