2lx7

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{{STRUCTURE_2lx7| PDB=2lx7 | SCENE= }}
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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A==
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===Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A===
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<StructureSection load='2lx7' size='340' side='right' caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LX7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2lx7 PDBsum]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2lx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T.]]
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[[Category: Acton, T]]
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[[Category: Dan, L.]]
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[[Category: Dan, L]]
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[[Category: Everett, J K.]]
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[[Category: Everett, J K]]
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[[Category: Janjua, H.]]
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[[Category: Janjua, H]]
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[[Category: Kennedy, M A.]]
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[[Category: Kennedy, M A]]
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[[Category: Kohan, E.]]
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[[Category: Kohan, E]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione, G T]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot, T A]]
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[[Category: Xiao, R.]]
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[[Category: Xiao, R]]
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[[Category: Yang, Y.]]
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[[Category: Yang, Y]]
[[Category: Protein binding]]
[[Category: Protein binding]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
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[[Category: Structural genomic]]
 
[[Category: Target hr8574a]]
[[Category: Target hr8574a]]

Revision as of 11:57, 18 December 2014

Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A

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