4hyt

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'''Unreleased structure'''
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{{STRUCTURE_4hyt| PDB=4hyt | SCENE= }}
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===Na,K-ATPase in the E2P state with bound ouabain and Mg2+ in the cation-binding site===
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The entry 4hyt is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/AT1A1_PIG AT1A1_PIG]] This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. [[http://www.uniprot.org/uniprot/AT1B1_PIG AT1B1_PIG]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
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Authors: Laursen, M., Yatime, L., Nissen, P., Fedosova, N.U.
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==About this Structure==
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[[4hyt]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HYT OCA].
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Description: Crystal structure of a membrane transporter
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[[Category: Sodium/potassium-exchanging ATPase]]
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[[Category: Sus scrofa]]
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[[Category: Fedosova, N U.]]
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[[Category: Laursen, M.]]
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[[Category: Nissen, P.]]
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[[Category: Yatime, L.]]
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[[Category: Hydrolase-membrane protein complex]]
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[[Category: Membrane transporter]]

Revision as of 10:27, 30 June 2013

Template:STRUCTURE 4hyt

Na,K-ATPase in the E2P state with bound ouabain and Mg2+ in the cation-binding site

Function

[AT1A1_PIG] This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. [AT1B1_PIG] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

About this Structure

4hyt is a 6 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

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