This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3is5
From Proteopedia
(Difference between revisions)
m (Protected "3is5" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | ==Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720== | |
| - | + | <StructureSection load='3is5' size='340' side='right' caption='[[3is5]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3is5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IS5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGME49_018720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3is5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3is5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3is5 RCSB], [http://www.ebi.ac.uk/pdbsum/3is5 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/3is5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Calcium/calmodulin-dependent protein kinase]] | [[Category: Calcium/calmodulin-dependent protein kinase]] | ||
[[Category: Toxoplasma gondii]] | [[Category: Toxoplasma gondii]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Artz, J D | + | [[Category: Artz, J D]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Cossar, D | + | [[Category: Cossar, D]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Hui, R | + | [[Category: Hui, R]] |
| - | [[Category: Hutchinson, A | + | [[Category: Hutchinson, A]] |
| - | [[Category: Kozieradzki, I | + | [[Category: Kozieradzki, I]] |
| - | [[Category: Lin, Y H | + | [[Category: Lin, Y H]] |
| - | [[Category: MacKenzie, F | + | [[Category: MacKenzie, F]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Senisterra, G | + | [[Category: Senisterra, G]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Wernimont, A K | + | [[Category: Wernimont, A K]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cdpk]] | [[Category: Cdpk]] | ||
| Line 28: | Line 47: | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
| - | [[Category: Toxoplasma gondii]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 17:17, 18 December 2014
Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720
| |||||||||||
Categories: Calcium/calmodulin-dependent protein kinase | Toxoplasma gondii | Arrowsmith, C H | Artz, J D | Bochkarev, A | Bountra, C | Cossar, D | Edwards, A M | Hui, R | Hutchinson, A | Kozieradzki, I | Lin, Y H | MacKenzie, F | Structural genomic | Senisterra, G | Weigelt, J | Wernimont, A K | Atp-binding | Cdpk | Kinase | Nucleotide-binding | Parasitology | Serine/threonine-protein kinase | Sgc | Transferase
