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Eukaryotic initiation factor

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===EIF1===
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*EIF1
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[[2if1]], [[1d7q]] – hEIF1 – human – NMR<BR />
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**[[2if1]], [[1d7q]] – hEIF1 – human – NMR<BR />
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[[2ogh]] - yEIF1 – NMR<BR />
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**[[2ogh]] - yEIF1 – NMR<BR />
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===EIF2===
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*EIF2
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[[1kl9]] – hEIF2A<BR />
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**[[1kl9]] – hEIF2A<BR />
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[[1q8x ]]– hEIF2A - NMR<BR />
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**[[1q8x ]]– hEIF2A - NMR<BR />
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[[1si2]], [[1si3]], [[4ei3]], [[4f3t]] – hEIF2C PAZ domain + DNA<BR />
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**[[1si2]], [[1si3]], [[4ei3]], [[4f3t]] – hEIF2C PAZ domain + DNA<BR />
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[[3luk]] - hEIF2C MID domain <BR />
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**[[3luk]] - hEIF2C MID domain <BR />
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[[3lud]], [[3lug]], [[3luh]], [[3luj]], [[3qx8]], [[3qx9]] - hEIF2C MID domain + nucleotide<br />
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**[[3lud]], [[3lug]], [[3luh]], [[3luj]], [[3qx8]], [[3qx9]] - hEIF2C MID domain + nucleotide<br />
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[[1q46]] – yEIF2A – yeast<BR />
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**[[1q46]] – yEIF2A – yeast<BR />
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[[2a19]], [[2a1a]] – yEIF2A (mutant) + interferon-induced protein kinase<BR />
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**[[2a19]], [[2a1a]] – yEIF2A (mutant) + interferon-induced protein kinase<BR />
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[[3ecs]] – hEIF2B
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**[[3ecs]] – hEIF2B
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===EIF3===
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*EIF3
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[[2nlw]] - hEIF3B RNA recognition domain – NMR<BR />
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**[[2nlw]] - hEIF3B RNA recognition domain – NMR<BR />
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[[3ns5]], [[3ns6]] - yEIF3B RNA recognition domain<BR />
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**[[3ns5]], [[3ns6]] - yEIF3B RNA recognition domain<BR />
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[[2krb]] - hEIF3B RNA recognition domain + hEIF3J peptide<br />
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**[[2krb]] - hEIF3B RNA recognition domain + hEIF3J peptide<br />
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[[2cq0]] – hEIF3G RNA recognition domain – NMR<BR />
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**[[2cq0]] – hEIF3G RNA recognition domain – NMR<BR />
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[[3zwl]] - yEIF3I + EIF3B C terminal<BR />
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**[[3zwl]] - yEIF3I + EIF3B C terminal<BR />
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[[3bpj]] – hEIF3J<BR />
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**[[3bpj]] – hEIF3J<BR />
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[[1rz4]] – hEIF3K
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**[[1rz4]] – hEIF3K
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===EIF4===
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*EIF4
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[[1fuk]] – yEIF4A C terminal<BR />
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**[[1fuk]] – yEIF4A C terminal<BR />
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[[1fuu]] - yEIF4A mRNA helicase domain<BR />
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**[[1fuu]] - yEIF4A mRNA helicase domain<BR />
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[[2g9n]], [[3bor]] – hEIF4A DEAD domain<BR />
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**[[2g9n]], [[3bor]] – hEIF4A DEAD domain<BR />
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[[3ex7]], [[2xb2]] – hEIF4A + MAGO homolog + RNA-binding protein 8A + CASC3 + RNA<BR />
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**[[3ex7]], [[2xb2]] – hEIF4A + MAGO homolog + RNA-binding protein 8A + CASC3 + RNA<BR />
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[[2zu6]], [[3eiq]] – hEIF4A + programmed cell death protein<BR />
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**[[2zu6]], [[3eiq]] – hEIF4A + programmed cell death protein<BR />
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[[1wi8]], [[2j76]] – hEIF4B RNA recognition domain - NMR<BR />
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**[[1wi8]], [[2j76]] – hEIF4B RNA recognition domain - NMR<BR />
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[[1ejh]] – mEIF4E + EIF4G peptide + GDP – mouse<BR />
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**[[1ejh]] – mEIF4E + EIF4G peptide + GDP – mouse<BR />
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[[1ej1]], [[1l8b]] - mEIF4E + nucleotide<br />
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**[[1ej1]], [[1l8b]] - mEIF4E + nucleotide<br />
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[[2gpq]], [[3tf2]] – hEIF4E<BR />
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**[[2gpq]], [[3tf2]] – hEIF4E<BR />
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[[2wmc]] - EIF4E - pea<BR />
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**[[2wmc]] - EIF4E - pea<BR />
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[[2idr]] – wEIF4E – wheat<BR />
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**[[2idr]] – wEIF4E – wheat<BR />
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[[2idv]] - wEIF4E (mutant) + GDP<BR />
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**[[2idv]] - wEIF4E (mutant) + GDP<BR />
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[[1ipb]], [[1ipc]] - hEIF4E + nucleotide<br />
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**[[1ipb]], [[1ipc]] - hEIF4E + nucleotide<br />
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[[4dt6]], [[4dum]] – hEIF4E + inhibitor<BR />
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**[[4dt6]], [[4dum]] – hEIF4E + inhibitor<BR />
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[[2w97]] – hEIF4E + hEIF4G peptide<br />
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**[[2w97]] – hEIF4E + hEIF4G peptide<br />
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[[1wkw]] - hEIF4E + EIF4E-binding protein peptide + GDP<BR />
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**[[1wkw]] - hEIF4E + EIF4E-binding protein peptide + GDP<BR />
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[[2v8w]], [[2v8x]], [[2v8y]], [[3u7x]] - hEIF4E + EIF4E-binding protein peptide<br />
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**[[2v8w]], [[2v8x]], [[2v8y]], [[3u7x]] - hEIF4E + EIF4E-binding protein peptide<br />
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[[3am7]] - hEIF4E + EIF4E-binding protein peptide + nucleotide<br />
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**[[3am7]] - hEIF4E + EIF4E-binding protein peptide + nucleotide<br />
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[[1ej4]] - mEIF4E + EIF4E-binding protein peptide<br />
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**[[1ej4]] - mEIF4E + EIF4E-binding protein peptide<br />
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[[3hxg]], [[3hxi]] - EIF4E + EIF4E-binding protein peptide + GDP – ''Schistosoma mansoni''<BR />
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**[[3hxg]], [[3hxi]] - EIF4E + EIF4E-binding protein peptide + GDP – ''Schistosoma mansoni''<BR />
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[[3m93]], [[3m94]] - EIF4E + EIF4E-binding protein peptide + nucleotide – Pig roundworm<BR />
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**[[3m93]], [[3m94]] - EIF4E + EIF4E-binding protein peptide + nucleotide – Pig roundworm<BR />
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[[1ap8]] – yEIF4E + GDP – NMR<BR />
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**[[1ap8]] – yEIF4E + GDP – NMR<BR />
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[[1rf8]] - yEIF4E + yEIF4GI peptide + GDP<BR />
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**[[1rf8]] - yEIF4E + yEIF4GI peptide + GDP<BR />
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[[2vso]], [[2vsx]] - yEIF4E + yEIF4F<BR />
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**[[2vso]], [[2vsx]] - yEIF4E + yEIF4F<BR />
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[[3l6a]] - hEIF4GII C terminal<BR />
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**[[3l6a]] - hEIF4GII C terminal<BR />
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[[1ug3]] – hEIF4GI C terminal (mutant) <BR />
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**[[1ug3]] – hEIF4GI C terminal (mutant)<br />
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[[1hu3]], [[3d3m]] – hEIF4GII middle domain<BR />
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**[[1hu3]], [[3d3m]] – hEIF4GII middle domain<br />
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[[2dng]] – hEIF4H RNA recognition domain – NMR<BR />
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**[[2dng]] – hEIF4H RNA recognition domain – NMR<br />
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===EIF5===
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*EIF5
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[[1eif]], [[2eif]] – EIF5A – ''Methanocaldococcus janaschii''<BR />
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**[[1eif]], [[2eif]] – EIF5A – ''Methanocaldococcus janaschii''<br />
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[[1x6o]] – EIF5A – ''Leishmania braziliensis''<BR />
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**[[1x6o]] – EIF5A – ''Leishmania braziliensis''<br />
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[[1xtd]] - EIF5A – ''Leishmania mexicana''<BR />
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**[[1xtd]] - EIF5A – ''Leishmania mexicana''<br />
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[[3hks]] – EIF5A – ''Arabidopsis thaliana''<BR />
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**[[3hks]] – EIF5A – ''Arabidopsis thaliana''<br />
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[[3cpf]] - hEIF<BR />
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**[[3cpf]] - hEIF<br />
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[[2ful]] – yEIF5 C terminal<BR />
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**[[2ful]] – yEIF5 C terminal<br />
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[[2iu1]] - hEIF5 C terminal<BR />
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**[[2iu1]] - hEIF5 C terminal<br />
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[[2g2k]] – hEIF5 N terminal (mutant) – NMR<BR />
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**[[2g2k]] – hEIF5 N terminal (mutant) – NMR<br />
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[[2e9h]] – hEIF5 – NMR<BR />
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**[[2e9h]] – hEIF5 – NMR<br />
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[[3cpf]] – hEIF5A<BR />
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**[[3cpf]] – hEIF5A<br />
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[[3er0]] - yEIF5A
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**[[3er0]] - yEIF5A<br />
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===EIF6===
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*EIF6
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[[1g62]] – yEIF6 <BR />
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**[[1g62]] – yEIF6 <br />
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[[2x7n]] – yEIF6S + sarcin-ricin loop + ribosomal protein L23 + ribosomal protein L24
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**[[2x7n]] – yEIF6S + sarcin-ricin loop + ribosomal protein L23 + ribosomal protein L24<br />
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}}
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[[Category:Topic Page]]
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Revision as of 12:07, 24 November 2014

Template:STRUCTURE 1ipb



Eukaryotic initiation factors (EIF) are involved in the initiation of protein translation. They form a complex with the small subunit of the ribosome and Met-tRNA which scans the mRNA and recognizes the initiation codon AUG. For details on EIF4 see C-terminal portion of human eIF4GI.

3D structures of eukaryotic initiation factor

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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