3kos

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Revision as of 02:32, 4 April 2013

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Template:STRUCTURE 3kos

Contents 1 Structure of the AmpR effector binding domain from Citrobacter freundii 2 Function 3 About this Structure 4 Reference

Structure of the AmpR effector binding domain from Citrobacter freundii

Template:ABSTRACT PUBMED 20594961

Function

[AMPR_CITFR] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.

About this Structure

3kos is a 1 chain structure with sequence from Citrobacter freundii. Full crystallographic information is available from OCA.

Reference

• Balcewich MD, Reeve TM, Orlikow EA, Donald LJ, Vocadlo DJ, Mark BL. Crystal structure of the AmpR effector binding domain provides insight into the molecular regulation of inducible ampc beta-lactamase. J Mol Biol. 2010 Jul 30;400(5):998-1010. Epub 2010 May 31. PMID:20594961 doi:10.1016/j.jmb.2010.05.040