3l1e

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Template:STRUCTURE 3l1e

Contents

Bovine AlphaA crystallin Zinc Bound

Template:ABSTRACT PUBMED 20440841

Function

[CRYAA_BOVIN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.

About this Structure

3l1e is a 1 chain structure with sequence from Bos taurus. The July 2010 RCSB PDB Molecule of the Month feature on Crystallins by David Goodsell is 10.2210/rcsb_pdb/mom_2010_7. Full crystallographic information is available from OCA.

Reference

  • Laganowsky A, Benesch JL, Landau M, Ding L, Sawaya MR, Cascio D, Huang Q, Robinson CV, Horwitz J, Eisenberg D. Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci. 2010 May;19(5):1031-43. PMID:20440841 doi:10.1002/pro.380

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OCA

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