3ku9

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Revision as of 20:08, 4 April 2013

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Template:STRUCTURE 3ku9

Contents 1 X-ray structure of the mutant lys300met of polyamine oxidase from zea mays in complex with spermine 2 Function 3 About this Structure 4 Reference

X-ray structure of the mutant lys300met of polyamine oxidase from zea mays in complex with spermine

Template:ABSTRACT PUBMED 021205212

Function

[PAO_MAIZE] Catalyzes the oxidation of the secondary amino group of polyamines (spermine, spermidine and their acetyl derivatives). Plays an important role in the regulation of polyamine intracellular concentration.

About this Structure

3ku9 is a 2 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

• Fiorillo A, Federico R, Polticelli F, Boffi A, Mazzei F, Di Fusco M, Ilari A, Tavladoraki P. The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. FEBS J. 2011 Mar;278(5):809-21. doi: 10.1111/j.1742-4658.2010.08000.x., Epub 2011 Jan 25. PMID:21205212 doi:10.1111/j.1742-4658.2010.08000.x