3l4u

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Template:STRUCTURE 3l4u

Contents

Crystal complex of N-terminal Human Maltase-Glucoamylase with de-O-sulfonated kotalanol

Template:ABSTRACT PUBMED 20039683

Function

[MGA_HUMAN] May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing.

About this Structure

3l4u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sim L, Jayakanthan K, Mohan S, Nasi R, Johnston BD, Pinto BM, Rose DR. New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry. 2010 Jan 26;49(3):443-51. PMID:20039683 doi:10.1021/bi9016457

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OCA

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