2e7y
From Proteopedia
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| - | [[Image:2e7y.jpg|left|200px]] | + | [[Image:2e7y.jpg|left|200px]] |
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| - | '''High resolution structure of T. maritima tRNase Z''' | + | {{Structure |
| + | |PDB= 2e7y |SIZE=350|CAPTION= <scene name='initialview01'>2e7y</scene>, resolution 1.97Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=PGO:1,2-PROPANEDIOL'>PGO</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Ribonuclease_Z Ribonuclease Z], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''High resolution structure of T. maritima tRNase Z''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2E7Y is a [ | + | 2E7Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E7Y OCA]. |
==Reference== | ==Reference== | ||
| - | The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes., Ishii R, Minagawa A, Takaku H, Takagi M, Nashimoto M, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt, 8):637-41. Epub 2007 Jul 21. PMID:[http:// | + | The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes., Ishii R, Minagawa A, Takaku H, Takagi M, Nashimoto M, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt, 8):637-41. Epub 2007 Jul 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17671357 17671357] |
[[Category: Ribonuclease Z]] | [[Category: Ribonuclease Z]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
[[Category: metallo-beta-lactamse]] | [[Category: metallo-beta-lactamse]] | ||
| - | [[Category: national project on protein structural and functional | + | [[Category: national project on protein structural and functional analyse]] |
[[Category: nppsfa]] | [[Category: nppsfa]] | ||
[[Category: riken structural genomics/proteomics initiative]] | [[Category: riken structural genomics/proteomics initiative]] | ||
[[Category: rnase]] | [[Category: rnase]] | ||
[[Category: rsgi]] | [[Category: rsgi]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: trna maturation]] | [[Category: trna maturation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:36:31 2008'' |
Revision as of 14:36, 20 March 2008
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| , resolution 1.97Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Activity: | Ribonuclease Z, with EC number 3.1.26.11 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
High resolution structure of T. maritima tRNase Z
Overview
tRNA 3'-processing endoribonuclease (tRNase Z) is one of the enzymes involved in the 3'-end processing of precursor tRNAs and is a member of the metallo-beta-lactamase superfamily. tRNase Z crystal structures have revealed that the enzyme forms a dimer and has a characteristic domain, named a flexible arm or an exosite, which protrudes from the metallo-beta-lactamase core and is involved in tRNA binding. The refined structure of Thermotoga maritima tRNase Z has been determined at 1.97 A resolution, revealing the structure of the flexible arm and the zinc-bound active site. The structure of the flexible arm of T. maritima tRNase Z is distinct from those of the Bacillus subtilis and Escherichia coli tRNase Zs. A comparison of the three tRNase Z structures revealed differences in the dimer orientation, which may be related to the unique cleavage-site specificity of T. maritima tRNase Z.
About this Structure
2E7Y is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.
Reference
The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes., Ishii R, Minagawa A, Takaku H, Takagi M, Nashimoto M, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt, 8):637-41. Epub 2007 Jul 21. PMID:17671357
Page seeded by OCA on Thu Mar 20 16:36:31 2008
Categories: Ribonuclease Z | Single protein | Thermotoga maritima | Ishii, R. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Yokoyama, S. | PGO | SO4 | ZN | Hydrolase | Metallo-beta-lactamse | National project on protein structural and functional analyse | Nppsfa | Riken structural genomics/proteomics initiative | Rnase | Rsgi | Structural genomic | Trna maturation
