This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4i9m
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
{{STRUCTURE_4i9m| PDB=4i9m | SCENE= }} | {{STRUCTURE_4i9m| PDB=4i9m | SCENE= }} | ||
===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES=== | ===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES=== | ||
| + | {{ABSTRACT_PUBMED_23576432}} | ||
==Function== | ==Function== | ||
| Line 6: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4i9m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4i9m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cylindrocarpon_theobromicola Cylindrocarpon theobromicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9M OCA]. |
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023576432</ref><references group="xtra"/><references/> | ||
| + | [[Category: Cylindrocarpon theobromicola]] | ||
[[Category: Phosphatidylinositol diacylglycerol-lyase]] | [[Category: Phosphatidylinositol diacylglycerol-lyase]] | ||
| - | [[Category: Staphylococcus aureus subsp. aureus str. newman]] | ||
[[Category: Cheng, J.]] | [[Category: Cheng, J.]] | ||
[[Category: Gershenson, A.]] | [[Category: Gershenson, A.]] | ||
Revision as of 05:23, 23 October 2013
Contents |
Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES
Template:ABSTRACT PUBMED 23576432
Function
[PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.
About this Structure
4i9m is a 1 chain structure with sequence from Cylindrocarpon theobromicola. Full crystallographic information is available from OCA.
Reference
- Cheng J, Goldstein R, Gershenson A, Stec B, Roberts MF. The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J Biol Chem. 2013 May 24;288(21):14863-73. doi: 10.1074/jbc.M113.466532. Epub, 2013 Apr 10. PMID:23576432 doi:http://dx.doi.org/10.1074/jbc.M113.466532
