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3md1

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{{STRUCTURE_3md1| PDB=3md1 | SCENE= }}
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==Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)==
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===Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)===
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<StructureSection load='3md1' size='340' side='right' caption='[[3md1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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{{ABSTRACT_PUBMED_020438847}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3md1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MD1 FirstGlance]. <br>
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==Function==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[http://www.uniprot.org/uniprot/PUB1_YEAST PUB1_YEAST]] May be associated with hnRNA within the nucleus and remains associated during nucleocytoplasmic mRNA transport, once the proteins are in the cytoplasm, disassembly of PUB1-RNA complexes may occur prior to PAB1 binding and formation of a translationally competent RNP complex. Binds to polyadenylated RNA; prefers to bind poly(rU); binds to T-rich single-stranded DNA.
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3md3|3md3]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3md1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3md1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3md1 RCSB], [http://www.ebi.ac.uk/pdbsum/3md1 PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3md1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MD1 OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/3md1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cui, Y.]]
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[[Category: Cui, Y]]
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[[Category: Li, H.]]
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[[Category: Li, H]]
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[[Category: Li, Y.]]
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[[Category: Li, Y]]
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[[Category: Niu, L.]]
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[[Category: Niu, L]]
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[[Category: Shi, H.]]
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[[Category: Shi, H]]
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[[Category: Teng, M.]]
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[[Category: Teng, M]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Pub1]]
[[Category: Pub1]]

Revision as of 17:23, 18 December 2014

Crystal Structure of the Second RRM Domain of Yeast Poly(U)-Binding Protein (Pub1)

3md1, resolution 1.60Å

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