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3mcq

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{{STRUCTURE_3mcq| PDB=3mcq | SCENE= }}
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==Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution==
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===Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution===
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<StructureSection load='3mcq' size='340' side='right' caption='[[3mcq]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MCQ FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/Q1H3U4_METFK Q1H3U4_METFK]] Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity).[HAMAP-Rule:MF_02128]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mfla_0573 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=405 Methylobacillus flagellatus])</td></tr>
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[[3mcq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylobacillus_flagellatus Methylobacillus flagellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MCQ OCA].
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine-phosphate_kinase Thiamine-phosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.16 2.7.4.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mcq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mcq RCSB], [http://www.ebi.ac.uk/pdbsum/3mcq PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mcq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Methylobacillus flagellatus]]
[[Category: Methylobacillus flagellatus]]
[[Category: Thiamine-phosphate kinase]]
[[Category: Thiamine-phosphate kinase]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: Jcsg]]
 
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[[Category: Joint center for structural genomic]]
 
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[[Category: Protein structure initiative]]
 
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[[Category: Psi-2]]
 
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: Jcsg]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 17:54, 18 December 2014

Crystal structure of Thiamine-monophosphate kinase (Mfla_0573) from METHYLOBACILLUS FLAGELLATUS KT at 1.91 A resolution

3mcq, resolution 1.91Å

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