4k3s
From Proteopedia
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- | + | {{STRUCTURE_4k3s| PDB=4k3s | SCENE= }} | |
+ | ===E. coli sliding clamp in P1 crystal space group=== | ||
- | The | + | ==Function== |
+ | [[http://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA. | ||
- | + | ==About this Structure== | |
- | + | [[4k3s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K3S OCA]. | |
- | + | [[Category: DNA-directed DNA polymerase]] | |
+ | [[Category: Escherichia coli k-12]] | ||
+ | [[Category: Oakley, A J.]] | ||
+ | [[Category: Yin, Z.]] | ||
+ | [[Category: E. coli sliding clamp]] | ||
+ | [[Category: Transferase]] |
Revision as of 07:58, 2 May 2013
E. coli sliding clamp in P1 crystal space group
Function
[DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
About this Structure
4k3s is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.