3n0a

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Template:STRUCTURE 3n0a

Contents

Crystal structure of auxilin (40-400)

Template:ABSTRACT PUBMED 20826345

Function

[AUXI_BOVIN] Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles.[1]

About this Structure

3n0a is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Guan R, Han D, Harrison SC, Kirchhausen T. Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding. Structure. 2010 Sep 8;18(9):1191-8. PMID:20826345 doi:10.1016/j.str.2010.06.016
  1. Fotin A, Cheng Y, Grigorieff N, Walz T, Harrison SC, Kirchhausen T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature. 2004 Dec 2;432(7017):649-53. Epub 2004 Oct 24. PMID:15502813 doi:10.1038/nature03078

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OCA

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