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3mtl
From Proteopedia
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| - | + | ==Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804== | |
| - | + | <StructureSection load='3mtl' size='340' side='right' caption='[[3mtl]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3mtl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MTL FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FEF:(2Z,3E)-2,3-BIINDOLE-2,3(1H,1H)-DIONE+3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}'>FEF</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mtl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mtl RCSB], [http://www.ebi.ac.uk/pdbsum/3mtl PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/3mtl_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Cyclin-dependent kinase|Cyclin-dependent kinase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Cyclin-dependent kinase]] | [[Category: Cyclin-dependent kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Amos, A | + | [[Category: Amos, A]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Ayinampudi, V | + | [[Category: Ayinampudi, V]] |
| - | [[Category: Berridge, G | + | [[Category: Berridge, G]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Bullock, A | + | [[Category: Bullock, A]] |
| - | [[Category: Burgess-Brown, N | + | [[Category: Burgess-Brown, N]] |
| - | [[Category: Das, S | + | [[Category: Das, S]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Fedorov, O | + | [[Category: Fedorov, O]] |
| - | [[Category: Filippakopoulos, P | + | [[Category: Filippakopoulos, P]] |
| - | [[Category: Keates, T | + | [[Category: Keates, T]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Krojer, T | + | [[Category: Krojer, T]] |
| - | [[Category: Muniz, J | + | [[Category: Muniz, J]] |
| - | [[Category: Phillips, C | + | [[Category: Phillips, C]] |
| - | [[Category: Pike, A C.W | + | [[Category: Pike, A C.W]] |
| - | [[Category: Rellos, P | + | [[Category: Rellos, P]] |
| - | [[Category: Roos, A | + | [[Category: Roos, A]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Savitsky, P | + | [[Category: Savitsky, P]] |
| - | [[Category: Sharpe, T D | + | [[Category: Sharpe, T D]] |
| - | [[Category: Thangaratnarajah, C | + | [[Category: Thangaratnarajah, C]] |
| - | [[Category: Ugochukwu, E | + | [[Category: Ugochukwu, E]] |
| - | [[Category: Vollmar, M | + | [[Category: Vollmar, M]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Yue, W | + | [[Category: Yue, W]] |
| - | [[Category: Zhang, Y | + | [[Category: Zhang, Y]] |
[[Category: Indirubin]] | [[Category: Indirubin]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Pctaire1]] | [[Category: Pctaire1]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 17:54, 18 December 2014
Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804
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Categories: Cyclin-dependent kinase | Homo sapiens | Amos, A | Arrowsmith, C H | Ayinampudi, V | Berridge, G | Bountra, C | Bullock, A | Burgess-Brown, N | Das, S | Delft, F von | Edwards, A | Fedorov, O | Filippakopoulos, P | Keates, T | Knapp, S | Krojer, T | Muniz, J | Phillips, C | Pike, A C.W | Rellos, P | Roos, A | Structural genomic | Savitsky, P | Sharpe, T D | Thangaratnarajah, C | Ugochukwu, E | Vollmar, M | Weigelt, J | Yue, W | Zhang, Y | Indirubin | Kinase | Pctaire1 | Sgc | Transferase
