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3n95

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{{STRUCTURE_3n95| PDB=3n95 | SCENE= }}
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==Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2==
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===Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2===
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<StructureSection load='3n95' size='340' side='right' caption='[[3n95]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
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{{ABSTRACT_PUBMED_020966082}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3n95]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N95 FirstGlance]. <br>
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==Function==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAL:MALTOSE'>MAL</scene></td></tr>
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[[http://www.uniprot.org/uniprot/UCN2_HUMAN UCN2_HUMAN]] Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n93|3n93]], [[3n96|3n96]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Human CRFR2 alpha ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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[[3n95]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N95 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n95 RCSB], [http://www.ebi.ac.uk/pdbsum/3n95 PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Pal, K.]]
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[[Category: Pal, K]]
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[[Category: Pioszak, A A.]]
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[[Category: Pioszak, A A]]
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[[Category: Swaminathan, K.]]
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[[Category: Swaminathan, K]]
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[[Category: Xu, H E.]]
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[[Category: Xu, H E]]
[[Category: Class b-gpcr]]
[[Category: Class b-gpcr]]
[[Category: Crfr2 alpha extracellular domain]]
[[Category: Crfr2 alpha extracellular domain]]

Revision as of 18:01, 18 December 2014

Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2

3n95, resolution 2.72Å

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