3n8e

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m (Protected "3n8e" [edit=sysop:move=sysop])
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{{STRUCTURE_3n8e| PDB=3n8e | SCENE= }}
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==Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)==
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===Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)===
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<StructureSection load='3n8e' size='340' side='right' caption='[[3n8e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3n8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8E FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/GRP75_HUMAN GRP75_HUMAN]] Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GRP75, HSPA9, HSPA9B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n8e RCSB], [http://www.ebi.ac.uk/pdbsum/3n8e PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3n8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8E OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berg, S van der.]]
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[[Category: Berg, S van der]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova, T]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Schuler, H.]]
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[[Category: Schuler, H]]
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[[Category: Schutz, P.]]
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[[Category: Schutz, P]]
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[[Category: Siponen, M I.]]
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[[Category: Siponen, M I]]
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[[Category: Svensson, L.]]
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[[Category: Svensson, L]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L.]]
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[[Category: Tresaugues, L]]
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[[Category: Wahlberg, E.]]
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[[Category: Wahlberg, E]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M.]]
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[[Category: Welin, M]]
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[[Category: Wisniewska, M.]]
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[[Category: Wisniewska, M]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Helix]]
[[Category: Helix]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 
[[Category: Substrate binding domain]]
[[Category: Substrate binding domain]]

Revision as of 17:41, 18 December 2014

Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)

3n8e, resolution 2.80Å

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