4bj1

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m (Protected "4bj1" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4bj1| PDB=4bj1 | SCENE= }}
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===Crystal structure of Saccharomyces cerevisiae RIF2===
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{{ABSTRACT_PUBMED_23746845}}
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The entry 4bj1 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/RIF2_YEAST RIF2_YEAST]] Involved in transcriptional silencing and telomere length regulation. Its role in telomere length regulation results from either a block in elongation or promoting degradation of the telomere ends. Loss of RIF1 function results in derepression of an HMR silencer, whose ARS consensus element has been deleted, and in the elongation of telomeres. RAP1 may target the binding of RIF1 to silencers and telomeres.
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Authors: Shi, T., Bunker, R.D., Gut, H., Scrima, A., Thoma, N.H.
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==About this Structure==
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[[4bj1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BJ1 OCA].
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Description: Crystal structure of Saccharomyces cerevisiae RIF2
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==Reference==
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<ref group="xtra">PMID:023746845</ref><references group="xtra"/><references/>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Bunker, R D.]]
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[[Category: Gut, H.]]
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[[Category: Scrima, A.]]
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[[Category: Shi, T.]]
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[[Category: Thoma, N H.]]
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[[Category: Aaa+ fold]]
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[[Category: Dna binding protein]]
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[[Category: Genome stability]]
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[[Category: Telomere associated protein]]

Revision as of 15:39, 19 June 2013

Template:STRUCTURE 4bj1

Contents

Crystal structure of Saccharomyces cerevisiae RIF2

Template:ABSTRACT PUBMED 23746845

Function

[RIF2_YEAST] Involved in transcriptional silencing and telomere length regulation. Its role in telomere length regulation results from either a block in elongation or promoting degradation of the telomere ends. Loss of RIF1 function results in derepression of an HMR silencer, whose ARS consensus element has been deleted, and in the elongation of telomeres. RAP1 may target the binding of RIF1 to silencers and telomeres.

About this Structure

4bj1 is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  • Shi T, Bunker RD, Mattarocci S, Ribeyre C, Faty M, Gut H, Scrima A, Rass U, Rubin SM, Shore D, Thoma NH. Rif1 and Rif2 Shape Telomere Function and Architecture through Multivalent Rap1 Interactions. Cell. 2013 Jun 6;153(6):1340-53. doi: 10.1016/j.cell.2013.05.007. PMID:23746845 doi:10.1016/j.cell.2013.05.007

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OCA

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