3nyv
From Proteopedia
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| - | + | ==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180== | |
| - | + | <StructureSection load='3nyv' size='340' side='right' caption='[[3nyv]], [[Resolution|resolution]] 1.88Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3nyv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NYV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NYV FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTQ:4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE'>DTQ</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i79|3i79]], [[3i7b|3i7b]], [[3i7c|3i7c]], [[3n51|3n51]], [[3mwu|3mwu]], [[3ncg|3ncg]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nyv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nyv RCSB], [http://www.ebi.ac.uk/pdbsum/3nyv PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/3nyv_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Calcium-dependent protein kinase|Calcium-dependent protein kinase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Calcium/calmodulin-dependent protein kinase]] | [[Category: Calcium/calmodulin-dependent protein kinase]] | ||
[[Category: Toxoplasma gondii]] | [[Category: Toxoplasma gondii]] | ||
| - | [[Category: Larson, E T | + | [[Category: Larson, E T]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Merritt, E A | + | [[Category: Merritt, E A]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Bumped kinase inhibitor]] | [[Category: Bumped kinase inhibitor]] | ||
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[[Category: Calmodulin]] | [[Category: Calmodulin]] | ||
[[Category: Ef hand]] | [[Category: Ef hand]] | ||
| - | [[Category: Medical structural genomics of pathogenic protozoa]] | ||
[[Category: Msgpp]] | [[Category: Msgpp]] | ||
[[Category: Serine/threonine protein kinase]] | [[Category: Serine/threonine protein kinase]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 06:39, 19 December 2014
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with non-specific inhibitor WHI-P180
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Categories: Calcium/calmodulin-dependent protein kinase | Toxoplasma gondii | Larson, E T | Structural genomic | Merritt, E A | Atp-binding | Bumped kinase inhibitor | Calcium-binding | Calmodulin | Ef hand | Msgpp | Serine/threonine protein kinase | Transferase | Transferase-transferase inhibitor complex
