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Tubulin

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== 3D Structures of Tubulin ==
== 3D Structures of Tubulin ==
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''Update February 2013''
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
=== Tubulin ===
=== Tubulin ===
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[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
[[4drx]] - sTUBA+sTUBB + ankyrin repeat protein<br />
[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
[[4f6r]] - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein<br />
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[[2wbe]] – cTUBA1D+cTUBB2B+kinesin+AMPPNP – cow<br />
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[[2wbe]] – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine<br />
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[[3dco]] - cTUBA+cTUBB+kinesin-like NOD<br />
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[[3dco]] - bTUBA+bTUBB+kinesin-like NOD<br />
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[[1tvk]] - cTUBA+cTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
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[[1tvk]] - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography<br />
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[[3iz0]] - cTUBA+cTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
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[[3iz0]] - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy<br />
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[[3edl]] - cTUBA1D+cTUBB2B+kinesin motor domain<br />
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[[3edl]] - bTUBA1D+bTUBB2B+kinesin motor domain<br />
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[[2xrp]] - cTUBA1D+cTUBB2B+doublecortin <br />
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[[2xrp]] - bTUBA1D+bTUBB2B+doublecortin <br />
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[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – cTUBA1C+cTUBB2B+stathmin-like protein B3<br />
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[[3du7]], [[3e22]], [[1z2b]], [[1sa0]], [[1sa1]] – bTUBA1C+bTUBB2B+stathmin-like protein B3<br />
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[[1ffx]] - cTUBA+cTUBB+stathmin-like protein B3<br />
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[[1ffx]] - bTUBA+bTUBB+stathmin-like protein B3<br />
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[[1jff]] - cTUBA+cTUBB<br />
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[[1jff]] - bTUBA+bTUBB<br />
 +
[[4hna]] - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein<br />
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[[4ihj]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + ADP<br />
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[[4iij]], [[4i55]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase <br />
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[[4i50]], [[4i4t]] - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent<br />
[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br />
[[2p4n]] - hTUBA+hTUBB+kinesin heavy chain<br />
[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br />
[[2hxf]] - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig<br />
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[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
[[4abo]] - pTUBA+pTUBB+ microtubule integrity protein MAL3<br />
[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
[[1tub]] - pTUBA+pTUBB – electron diffraction<br />
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[[4aqv]], [[4aqw]] - bTUBA+bTUBB+kinesin-like KIF11 – bovine – Cryo EM<br />
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[[4aqv]], [[4aqw]] - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM<br />
[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
[[4atu]] - bTUBA1D+bTUBB2B+doublecortin – Cryo EM<br />
[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />
[[4atx]] - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM<br />

Revision as of 10:45, 8 August 2013

Image:1z5w.png
Crystal Structure of Tubulin 1z5w

Template:STRUCTURE 1z5w










Tubulin (TUB) is a constituent of microtubules in eukaryotes. Microtubules are assembled from dimers of α-tubulin (TUBA) and β-tubulin (TUBB) bound to GTP. γ-tubulin (TUBG) is part of the nucleation of microtubules. Human TUB contains several numbered subtypes. FtsZ (Filamenting temperature-sensitive mutant Z) is a prokaryotic homologue of TUB. The images at the left and at the right correspond to one representative Tubulin, i.e. the crystal structure of Tubulin (1z5w).

Contents

3D Structures of Tubulin

Updated on 08-August-2013

Tubulin

α-tubulin

2bto – PdTUBA+thioredoxin 1 – Prosthecobacter dejongeii

α-tubulin + β-tubulin

3hkb, 3hkc, 3hkd, 3hke, 3n2g, 3n2k, 3ryc, 3ryf, 3ryh, 3ryi – sTUBA+sTUBB+stathmin-like protein B3 – sheep
4f61 - sTUBA+sTUBB+stathmin-like protein R4
3ut5 - sTUBA+sTUBB+stathmin-like protein B3 + vinca peptide
4drx - sTUBA+sTUBB + ankyrin repeat protein
4f6r - sTUBA+sTUBB+stathmin-like protein R1 + ankyrin repeat protein
2wbe – bTUBA1D+bTUBB2B+kinesin+AMPPNP – bovine
3dco - bTUBA+bTUBB+kinesin-like NOD
1tvk - bTUBA+bTUBB+GDP+GTP+Epothilone A – electron crystallography
3iz0 - bTUBA+bTUBB+hNDC80/SPC25+hNUF2/SPC24 – electron microscopy
3edl - bTUBA1D+bTUBB2B+kinesin motor domain
2xrp - bTUBA1D+bTUBB2B+doublecortin
3du7, 3e22, 1z2b, 1sa0, 1sa1 – bTUBA1C+bTUBB2B+stathmin-like protein B3
1ffx - bTUBA+bTUBB+stathmin-like protein B3
1jff - bTUBA+bTUBB
4hna - bTUBA+bTUBB + kinesin heavy chain + ankyrin repeat protein
4ihj - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + ADP
4iij, 4i55 - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase
4i50, 4i4t - bTUBA+bTUBB+stathmin-like protein B3 + tubulin tyrosine ligase + anti-cancer agent
2p4n - hTUBA+hTUBB+kinesin heavy chain
2hxf - pTUBA+pTUBB+kinesin-like KIF1A+AMPPNP – pig
2hxh - pTUBA+pTUBB+kinesin-like KIF1A+ADP
1ia0 - pTUBA+pTUBB+kinesin-like KIF1A+ATP
4abo - pTUBA+pTUBB+ microtubule integrity protein MAL3
1tub - pTUBA+pTUBB – electron diffraction
4aqv, 4aqw - bTUBA+bTUBB+kinesin-like KIF11 – Cryo EM
4atu - bTUBA1D+bTUBB2B+doublecortin – Cryo EM
4atx - bTUBA1D+bTUBB2B+kinesin motor domain – Cryo EM
2btq – PdTUBA+PdTUBB
4ffb - TUBA+TUBB (mutant) + protein STU2 - yeast

γ-tubulin

3cb2 – hTUBG1+GDP
1z5v - hTUBG1+GTPgS
1z5w - hTUBG1+GTP

FtsZ

2rhh, 2rhj – BsFtsZ+SO4 – Bacillus subtilis
2rhl - BsFtsZ+GDP
2rho - BsFtsZ+GDP+GTP-gamma-S
2vxy, 2vam – BsFtsZ
2ve8 – PaFtsZ gamma domain – Pseudomonas aeruginosa
2ve9 - PaFtsZ gamma domain+DNA
2vaw – PaFtsZ+GDP
1ofu - PaFtsZ+SULA
2r75 - AaFtsZ+8-morpholino-GTP – Aquifex aeolicus
2r6r - AaFtsZ
2q1x, 1rq2 - MtFtsZ+citrate – Mycobacterium tuberculosis
2q1y, 1rlu - MtFtsZ+GTP-gamma-S
1rq7 - MtFtsZ+GDP
2vap – MjFtsZ+GDP – Methancaldococcus jannaschii
1w58 - MjFtsZ+GMPCPP
1w59, 1fsz – MjFtsZ
1w5a - MjFtsZ+MgGTP
1w5b - MjFtsZ+GTP
1w5e, 1w5f – MjFtsZ (mutant)

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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