Sandbox Reserved 693
From Proteopedia
(Difference between revisions)
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'''6-Mercaptopurine activity and targeting''' <br> | '''6-Mercaptopurine activity and targeting''' <br> | ||
- | <Structure load='1hmp' size='500' frame='true' align='right' caption='GMP bound to HGPRT' scene=' | + | <Structure load='1hmp' size='500' frame='true' align='right' caption='GMP bound to HGPRT' scene='GMP' /> |
[[Image:Mercaptopurine.png]] | [[Image:Mercaptopurine.png]] | ||
- | 6-Mercaptopurine (6-MP) is an anti-cancer drug used for decades to treat acute lymphoblastic leukemia, and in recent years for other conditions such as inflammatory bowel disease. | + | 6-Mercaptopurine (6-MP) is an anti-cancer drug used for decades to treat acute lymphoblastic leukemia, and in recent years for other conditions such as inflammatory bowel disease. The drug is a purine derivative that resembles Guanosine, except that it has a thiol on the C6 of the base ring structure instead of a carbonyl, and is missing the amine on C2. |
Revision as of 21:33, 28 April 2013
This Sandbox is Reserved from 30/01/2013, through 30/12/2013 for use in the course "Biochemistry II" taught by Hannah Tims at the Messiah College. This reservation includes Sandbox Reserved 686 through Sandbox Reserved 700. |
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6-Mercaptopurine activity and targeting
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6-Mercaptopurine (6-MP) is an anti-cancer drug used for decades to treat acute lymphoblastic leukemia, and in recent years for other conditions such as inflammatory bowel disease. The drug is a purine derivative that resembles Guanosine, except that it has a thiol on the C6 of the base ring structure instead of a carbonyl, and is missing the amine on C2.
3ns1 - 6mp bound to bovine xanthine oxidase 2bzg - TPMT