4jvy

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'''Unreleased structure'''
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{{STRUCTURE_4jvy| PDB=4jvy | SCENE= }}
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===Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA===
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{{ABSTRACT_PUBMED_23630077}}
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The entry 4jvy is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/GLD1_CAEEL GLD1_CAEEL]] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.
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Authors: Teplova, M., Hafner, M., Teplov, D., Essig, K., Tuschl, T., Patel, D.J.
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==About this Structure==
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[[4jvy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVY OCA].
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Description: Structure of the STAR (signal transduction and activation of RNA)domain of GLD-1 bound to RNA
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[[Category: Caenorhabditis elegans]]
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[[Category: Essig, K.]]
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[[Category: Hafner, M.]]
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[[Category: Patel, D J.]]
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[[Category: Teplov, D.]]
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[[Category: Teplova, M.]]
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[[Category: Tuschl, T.]]
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[[Category: Kh domain]]
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[[Category: Rna binding protein]]
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[[Category: Rna regulation]]
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[[Category: Star domain]]
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[[Category: Translational repression. rna binding protein]]

Revision as of 07:39, 8 May 2013

Template:STRUCTURE 4jvy

Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA

Template:ABSTRACT PUBMED 23630077

Function

[GLD1_CAEEL] Germ line-specific tumor suppressor essential for oogenesis. Controls the spatial pattern of translation of multiple oogenesis specific mRNAs (e.g. yolk receptor rme-2) by repression of translation during early meiotic prophase (leptotene to pachytene) and then derepression of translation during diplotene/ diakinesis, following its degradation. Also functions to promote the male sexual fate in the hermaphrodite germline but not the male germline. Functions redundantly with gld-2 to promote the initiation of meiotic development and/or inhibit stem cell proliferation.

About this Structure

4jvy is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

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OCA

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