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4k6l
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4k6l| PDB=4k6l | SCENE= }} | |
| + | ===Structure of Typhoid Toxin=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CDTB_SALTI CDTB_SALTI]] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. | ||
| - | + | ==About this Structure== | |
| - | + | [[4k6l]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6L OCA]. | |
| - | + | [[Category: Salmonella enterica subsp. enterica serovar typhi]] | |
| + | [[Category: Galan,J.]] | ||
| + | [[Category: Gao,X.]] | ||
| + | [[Category: Song,J.]] | ||
| + | [[Category: Bacterial toxin]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Sugar]] | ||
| + | [[Category: Toxin]] | ||
Revision as of 05:04, 18 July 2013
Structure of Typhoid Toxin
Function
[CDTB_SALTI] Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
About this Structure
4k6l is a 7 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhi. Full crystallographic information is available from OCA.
