3of3
From Proteopedia
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| - | + | ==Crystal structure of PNP with an inhibitor DADME_immH from Vibrio cholerae== | |
| - | + | <StructureSection load='3of3' size='340' side='right' caption='[[3of3]], [[Resolution|resolution]] 1.83Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3of3]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OF3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">deoD, deoD1, VC_2347 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3of3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3of3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3of3 RCSB], [http://www.ebi.ac.uk/pdbsum/3of3 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/3of3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Purine-nucleoside phosphorylase]] | [[Category: Purine-nucleoside phosphorylase]] | ||
[[Category: Vibrio cholerae]] | [[Category: Vibrio cholerae]] | ||
| - | [[Category: Almo, S C | + | [[Category: Almo, S C]] |
| - | [[Category: Burley, S K | + | [[Category: Burley, S K]] |
| - | [[Category: Kim, J | + | [[Category: Kim, J]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Ramagopal, U A | + | [[Category: Ramagopal, U A]] |
| - | [[Category: New | + | [[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]] |
| - | + | ||
[[Category: Phophoryl transferase]] | [[Category: Phophoryl transferase]] | ||
[[Category: Phosphate]] | [[Category: Phosphate]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Purine nucleoside]] | [[Category: Purine nucleoside]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 12:52, 6 November 2014
Crystal structure of PNP with an inhibitor DADME_immH from Vibrio cholerae
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Categories: Purine-nucleoside phosphorylase | Vibrio cholerae | Almo, S C | Burley, S K | Kim, J | Structural genomic | Ramagopal, U A | NYSGXRC, New York SGX Research Center for Structural Genomics | Phophoryl transferase | Phosphate | PSI, Protein structure initiative | Purine nucleoside | Transferase
