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3oit
From Proteopedia
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{{STRUCTURE_3oit| PDB=3oit | SCENE= }} | {{STRUCTURE_3oit| PDB=3oit | SCENE= }} | ||
===Crystal structure of curcuminoid synthase CUS from Oryza sativa=== | ===Crystal structure of curcuminoid synthase CUS from Oryza sativa=== | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/CUS_ORYSJ CUS_ORYSJ]] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.<ref>PMID:21041675</ref> | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3oit]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3oit]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_rice Japanese rice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OIT OCA]. |
| - | [[Category: | + | |
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021117241</ref><references group="xtra"/><references/> | ||
| + | [[Category: Japanese rice]] | ||
[[Category: Horinouchi, S.]] | [[Category: Horinouchi, S.]] | ||
[[Category: Imai, F L.]] | [[Category: Imai, F L.]] | ||
Revision as of 15:17, 3 March 2014
Contents |
Crystal structure of curcuminoid synthase CUS from Oryza sativa
Function
[CUS_ORYSJ] Plant-specific type III polyketide synthase (PKS) that catalyzes the one-pot formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin by the condensation of two molecules of 4-coumaroyl-CoA and one molecule of malonyl-CoA.[1]
About this Structure
3oit is a 2 chain structure with sequence from Japanese rice. Full crystallographic information is available from OCA.
Reference
- Miyazono K, Um J, Imai FL, Katsuyama Y, Ohnishi Y, Horinouchi S, Tanokura M. Crystal structure of curcuminoid synthase CUS from Oryza sativa. Proteins. 2011 Feb;79(2):669-73. doi: 10.1002/prot.22888. PMID:21117241 doi:http://dx.doi.org/10.1002/prot.22888
- ↑ Morita H, Wanibuchi K, Nii H, Kato R, Sugio S, Abe I. Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19778-83. Epub 2010 Nov 1. PMID:21041675 doi:http://dx.doi.org/10.1073/pnas.1011499107
