3opw

From Proteopedia

Revision as of 08:28, 2 May 2013 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 08:28, 2 May 2013 (edit) (undo) OCA (Talk | contribs) m (Protected "3opw" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 08:28, 2 May 2013

proteopedia linkproteopedia link

Template:STRUCTURE 3opw

Contents 1 Crystal Structure of the Rph1 catalytic core 2 Function 3 About this Structure 4 Reference

Crystal Structure of the Rph1 catalytic core

Template:ABSTRACT PUBMED 21067515

Function

[RPH1_YEAST] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.^{[1] [2]}

About this Structure

3opw is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

• Chang Y, Wu J, Tong XJ, Zhou JQ, Ding J. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism. Biochem J. 2010 Nov 10. PMID:21067515 doi:10.1042/BJ20101418

1. ↑ Jang YK, Wang L, Sancar GB. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol Cell Biol. 1999 Nov;19(11):7630-8. PMID:10523651
2. ↑ Kim EM, Jang YK, Park SD. Phosphorylation of Rph1, a damage-responsive repressor of PHR1 in Saccharomyces cerevisiae, is dependent upon Rad53 kinase. Nucleic Acids Res. 2002 Feb 1;30(3):643-8. PMID:11809875