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3oz5

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Template:STRUCTURE 3oz5

S-Methyl Carbocyclic LNA

Template:ABSTRACT PUBMED 20886816

About this Structure

3oz5 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Seth PP, Allerson CR, Berdeja A, Siwkowski A, Pallan PS, Gaus H, Prakash TP, Watt AT, Egli M, Swayze EE. An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. J Am Chem Soc. 2010 Oct 27;132(42):14942-50. PMID:20886816 doi:10.1021/ja105875e

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OCA

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