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2g5o

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[[Image:2g5o.gif|left|200px]]<br /><applet load="2g5o" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2g5o.gif|left|200px]]
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caption="2g5o, resolution 2.30&Aring;" />
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'''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide'''<br />
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{{Structure
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|PDB= 2g5o |SIZE=350|CAPTION= <scene name='initialview01'>2g5o</scene>, resolution 2.30&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=DRQ:(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL'>DRQ</scene>
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|ACTIVITY=
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|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2G5O is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DRQ:'>DRQ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G5O OCA].
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2G5O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G5O OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: lbd]]
[[Category: lbd]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:28:22 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:00:44 2008''

Revision as of 15:00, 20 March 2008


PDB ID 2g5o

Drag the structure with the mouse to rotate
, resolution 2.30Å
Ligands:
Gene: ESR1, ESR, NR3A1 (Homo sapiens)
Coordinates: save as pdb, mmCIF, xml



Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide


Disease

Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]

About this Structure

2G5O is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 17:00:44 2008

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