4bl6

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m (Protected "4bl6" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4bl6| PDB=4bl6 | SCENE= }}
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===Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein===
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{{ABSTRACT_PUBMED_23723415}}
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The entry 4bl6 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/BICD_DROME BICD_DROME]] This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. BicD mutations cause Nanos mislocalization and thus bicaudal development.
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Authors: Liu, Y., Salter, H.K., Holding, A.N., Johnson, C.M., Stephens, E., Lukavsky, P.J., Walshaw, J., Bullock, S.L.
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==About this Structure==
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[[4bl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BL6 OCA].
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Description: Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein
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==Reference==
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<ref group="xtra">PMID:023723415</ref><references group="xtra"/><references/>
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[[Category: Drosophila melanogaster]]
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[[Category: Bullock, S L.]]
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[[Category: Holding, A N.]]
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[[Category: Johnson, C M.]]
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[[Category: Liu, Y.]]
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[[Category: Lukavsky, P J.]]
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[[Category: Salter, H K.]]
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[[Category: Stephens, E.]]
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[[Category: Walshaw, J.]]
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[[Category: Cargo binding]]
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[[Category: Protein transport]]

Revision as of 13:46, 19 June 2013

Template:STRUCTURE 4bl6

Contents

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein

Template:ABSTRACT PUBMED 23723415

Function

[BICD_DROME] This protein is essential for differentiation. It may play a role in localizing of Nanos (a maternal determinant) activity in oocytes. BicD mutations cause Nanos mislocalization and thus bicaudal development.

About this Structure

4bl6 is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Liu Y, Salter HK, Holding AN, Johnson CM, Stephens E, Lukavsky PJ, Walshaw J, Bullock SL. Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein. Genes Dev. 2013 Jun 1;27(11):1233-46. doi: 10.1101/gad.212381.112. Epub 2013 May , 30. PMID:23723415 doi:10.1101/gad.212381.112

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OCA

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