4kg8

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m (Protected "4kg8" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4kg8| PDB=4kg8 | SCENE= }}
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===Crystal structure of light mutant===
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The entry 4kg8 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
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Authors: Liu, W., Zhan, C., Rajesh, P., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
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==About this Structure==
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[[4kg8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG8 OCA].
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Description: Crystal structure of light mutant
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[[Category: Homo sapiens]]
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[[Category: Almo, S C.]]
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[[Category: Bonanno, J B.]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
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[[Category: Liu, W.]]
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[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
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[[Category: Nathenson, S G.]]
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[[Category: Rajesh, P.]]
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[[Category: Zhan, C.]]
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[[Category: Atoms-to-animals: the immune function network]]
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[[Category: Bind tnf receptor hvem and ltbr]]
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[[Category: Cytokine]]
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[[Category: Dcr3]]
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[[Category: Hvem]]
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[[Category: Ifn]]
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[[Category: Immunity]]
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[[Category: Jelly-roll fold]]
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[[Category: Ltbr]]
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[[Category: Membrane]]
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[[Category: N-glycosylation]]
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[[Category: New york structural genomics research consortium]]
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[[Category: Nysgrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Secreted protein]]
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[[Category: Structural genomic]]
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[[Category: Tnf superfamily]]

Revision as of 21:03, 7 August 2013

Template:STRUCTURE 4kg8

Crystal structure of light mutant

Function

[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

About this Structure

4kg8 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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OCA

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