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4hlo
From Proteopedia
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| - | {{STRUCTURE_4hlo| PDB=4hlo | SCENE= }}
| + | #REDIRECT [[4osx]] This PDB entry is obsolete and replaced by 4osx |
| - | ===Structure of uncleaved glycine-bound human L-Asparaginase protein===
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| - | {{ABSTRACT_PUBMED_23601642}}
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| - | ==Function==
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| - | [[http://www.uniprot.org/uniprot/ASGL1_HUMAN ASGL1_HUMAN]] Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.<ref>PMID:19839645</ref> | + | |
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| - | ==About this Structure==
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| - | [[4hlo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HLO OCA].
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| - | ==Reference==
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| - | <references group="xtra"/><references/>
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| - | [[Category: Asparaginase]]
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| - | [[Category: Homo sapiens]]
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| - | [[Category: Lavie, A.]]
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| - | [[Category: Nomme, J.]]
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| - | [[Category: Homodimer]]
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| - | [[Category: Hydrolase]]
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| - | [[Category: Ntn enzyme]]
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Current revision
- REDIRECT 4osx This PDB entry is obsolete and replaced by 4osx
